Contact Us: Sales@finabio.com

Amino-Dextran

aminoAmino-Dextran (AmDex, AECM-dextran) consists of dextran functionalized with primary amines. Our AmDex is prepared from dextran using a protocol yielding a stable, amino functionalized dextran that is superior to the more commonly used reductive amination methods. The molecular weight profile of Fina Biosolutions’ AmDex is essentially unchanged from the starting dextran, as determined by analytical size exclusion chromatography. The product is desalted and lyophilized. We do extensive processing and testing to ensure that free amino reagent is removed, resulting in a consistent product with minimal lot-to-lot variation.

We have found that many commercial lots of amino-dextran contain variable amounts of dextran and that the amine content is often incorrect. Furthermore, the actual polymer molecular weight distributions of these preparations can vary extensively from the indicated molecular weight. These issues can mean that optimization data is based on incorrect information. Lot-to-lot variations means that protocols may need to be revised when a new lot of AmDex is used.

We take care to ensure that we provide a consistent product. Each batch of amino-dextran polymer is evaluated for molecular weight distribution and for the amine content, expressed as amines/polymer as well as assayed to determine the weight percent dextran. A certificate of analysis is provided for each lot.

Amino-dextrans are available in molecular weights from 3.5 kDa to 2000 kDa in a variety of amine ratios. Custom polymers can be synthesized to match your needs.

amdex

 

Size exclusion chromatography of 70 kDa dextrans.
Overlay of dextran and AmDex.

White paper: Characterization of Fina Biosolutions’ Amino-Dextran

 


Pricing

For bulk and custom quotes contact: Sales@finabio.com

Amino Dextran MW x amines/polymer 3.5 kDa Product Details, click here.
Amino Dextran MW x amines/polymer 6 kDa Product Details, click here.
Amino Dextran MW x amines/polymer 10 kDa Product Details, click here.
Amino Dextran MW x amines/polymer 20 kDa Product Details, click here.
Amino Dextran MW x amines/polymer 40 kDa Product Details, click here.
Amino Dextran MW x amines/polymer 70 kDa Product Details, click here.
Amino Dextran MW x amines/polymer 100 kDa Product Details, click here.
Amino Dextran MW x amines/polymer 250 kDa Product Details, click here.
Amino Dextran MW x amines/polymer 500 kDa Product Details, click here.
Amino Dextran MW x amines/polymer 2000 kDa Product Details, click here.

Safety & Handling

Non-toxic. Avoid contact with skin and eyes. Product may be discarded down drain. Product is intended for research purposes only.

News

  • About FinaBio
    Whitepaper
    Characterization of Fina Biosolutions’ Amino-Dextran
  • About FinaBio

Address

9430 Key West Ave., Suite 200
Rockville, MD 20850
877-346-2246 (877-FinaBio)
301-633-0464 (Andrew Lees, Scientific Director)
Finabio.net
ALees@FinaBio.com

About Us

Fina Biosolutions, LLC was founded in 2006 by Dr. Andrew Lees with an initial focus on helping emerging market vaccine manufacturers learn to make affordable conjugate vaccines. FinaBio has since grown to offer a variety of bioconjugation and protein services. The company is located in the heart of Maryland’s biotechnology corridor.