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Multi-angle Light Scattering (MALS)

 Absolute Molecular Weight Determination by Multi-angle Light Scattering (MALS)

Fina Biosolutions now offers size-exclusion chromatography combined with multiangle laser light scattering (SEC MALS) for the determination of absolute molecular weight of proteins, conjugates and polymers.  Unlike other techniques, MALS determines the absolute molecular weight without the need for molecular weight standards.  FinaBio’s SEC MALS is capable of determining molecular weights up to 50,000 kDa.

Examples of applications for MALS:

  • Antibody dimer and aggregate determination
  • Polymer molecular weight and polydispersity
  • Degree of protein pegylation
  • Carbohydrate ratios for conjugate vaccines


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    Characterization of Fina Biosolutions’ Amino-Dextran
  • About FinaBio


9430 Key West Ave., Suite 200
Rockville, MD 20850
877-346-2246 (877-FinaBio)
301-633-0464 (Andrew Lees, Scientific Director)

About Us

Fina Biosolutions, LLC was founded in 2006 by Dr. Andrew Lees with an initial focus on helping emerging market vaccine manufacturers learn to make affordable conjugate vaccines. FinaBio has since grown to offer a variety of bioconjugation and protein services. The company is located in the heart of Maryland’s biotechnology corridor.