
Specialty Immunoreagents are a collection of reagents mainly of interest to immunologists. These reagents originated from both our own research and requests from other scientists.
In June 2025, FinaBio acquired the remaining inventory of LGC Biosearch Technologies. To the extent possible, FinaBio is committed to support the immunology research community by continuing to supply the Biosearch legacy immunological reagents. Most will be kept in stock or can be synthesized in <1 month.
Please inquire if you don’t see the reagent listed or if a custom product is needed.
TNP-Dextran and TNP-Ficoll are classic T-cell independent model antigens. Due to the wide availability of TNP immunoreagents, they serve as useful models of natural T-cell independent antigens like polysaccharides.
TNP-LPS (trinitrophenyl-lipopolysaccharide) is primarily used as a model antigen in immunological research for investigating the mechanisms of immune responses, particularly those that do not require T cell help (T-independent responses).
TNP-OVA, TNP-BSA and TNP-KLH serve as T-cell dependent model antigens with the trinitrophenyl epitope. The set of TNP reagents also allows for the selection of a suitable ELISA antigen.
In addition to TNP, these reagents are also available with NP (4-hydroxy-3-nitrophenylacetate), NIP(4-Hydroxy-3-iodo-5-nitrophenylacetyl) and DNP (dinitrophenyl) epitopes.
Our phosphorylcholine (PC) conjugates are based on the method of Chesbro and Metzger (Biochem, 11:766, 1972) utilizing p-diazonium phenylphosphorylcholine. These are sometimes referred to as DPPC conjugates.
Phenylarsonate (Ars) conjugates are made by the method of Amkraut et al. (J Exp Med, 124:293, 1966.)
In contrast to other commercial heparin conjugates, ours utilize the terminal end of the polymer, resulting in minimum modification of the heparin.